Opportunity Information: Apply for 72067419RFA00005

The Karabo ea Bophelo (KB) Activity in Lesotho is a USAID/Southern Africa funding opportunity designed to support a five-year, nationwide effort to prevent new HIV infections and reduce vulnerability among two priority groups: orphans and vulnerable children (OVC) and adolescent girls and young women (AGYW). "Karabo ea Bophelo" translates to "a solution to good health," and the activity is structured to align closely with Lesotho's HIV mitigation and prevention priorities while strengthening community-level systems that help people access and stay connected to health and social services.

At its core, the KB Activity focuses on addressing the social, behavioral, and structural factors that contribute to HIV risk, especially for OVC and AGYW. This includes the kinds of challenges that often sit behind infection risk and poor health outcomes, such as gender inequality, economic vulnerability, limited access to youth-friendly services, stigma, and barriers that keep adolescents and vulnerable households from using prevention and sexual and reproductive health (SRH) services. A major emphasis is placed on expanding and improving access to comprehensive SRH services as a practical way to reduce new infections and strengthen prevention outcomes over time.

The activity is explicitly designed to support and complement the Government of Lesotho (GOL) multi-sector response to HIV, meaning it is not limited to clinical services alone. Instead, it aims to strengthen community platforms that can connect households and individuals to services, reinforce prevention messaging and risk reduction behaviors, and support the local rollout and scale-up of clinical interventions. In practical terms, this type of programming often involves coordinated community-based prevention, referral and linkage systems, support for vulnerable households, and interventions that reduce barriers to care, with the intention that clinical services are more accessible, better utilized, and more sustainable at district and community levels.

KB also sits within broader U.S. Government and global HIV targets. It contributes to USAID/Southern Africa's Regional Development Cooperation Strategy, specifically Development Objective 2, "Reduced impact of HIV/AIDS on the region." It is also framed as a contributor to PEPFAR and UNAIDS 95-95-95 goals, which aim to ensure that the vast majority of people living with HIV know their status, receive sustained treatment, and achieve viral suppression. While KB is prevention-focused, the link to 95-95-95 reflects the reality that effective community engagement and service linkage are essential to finding people earlier, keeping them in care, and supporting adherence, all of which ultimately reduces onward transmission.

Geographically, the KB Activity is intended to be implemented across all ten districts of Lesotho, which are also identified as PEPFAR priority areas. Applicants are expected to coordinate closely with services already funded by the GOL, PEPFAR, and other development partners, which signals a strong expectation for collaboration, avoidance of duplication, and integration with existing district-level and national systems. The shared goal highlighted in the announcement is to significantly reduce the number of new HIV infections in Lesotho by 2020 and beyond, positioning the activity as part of a longer-term prevention and resilience strategy rather than a short-term pilot.

From the grant administration perspective, this opportunity was released by USAID (Agency for International Development, South Africa; USAID-Pretoria) as a discretionary funding opportunity using a Cooperative Agreement mechanism. A Cooperative Agreement typically means USAID anticipates substantial involvement during implementation, such as joint planning, technical collaboration, or close monitoring and learning. The opportunity number is 72067419RFA00005, with a creation date of March 13, 2019 and an original closing date of April 18, 2019. The award ceiling listed is $35,000,000, and USAID expected to make one award. The activity category is Health, and the CFDA number referenced is 98.001. Eligibility is listed broadly as "Others," with further clarification intended in the full announcement under the additional eligibility information section.

  • The Agency for International Development, South Africa USAID-Pretoria in the health sector is offering a public funding opportunity titled "Karabo ea Bophelo (KB) Activity in Lesotho" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 98.001.
  • This funding opportunity was created on Mar 13, 2019.
  • Applicants must submit their applications by Apr 18, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $35,000,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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Frequently Asked Questions (FAQs): Karabo ea Bophelo (KB) Activity - Lesotho (USAID/Southern Africa)

1) What is the Karabo ea Bophelo (KB) Activity?

The Karabo ea Bophelo (KB) Activity is a USAID/Southern Africa funding opportunity for a five-year, nationwide effort in Lesotho focused on HIV prevention and reducing vulnerability. The activity is designed to align with Lesotho's HIV mitigation and prevention priorities and to strengthen community-level systems that connect people to health and social services.

2) What does "Karabo ea Bophelo" mean?

"Karabo ea Bophelo" translates to "a solution to good health."

3) What are the main goals of the KB Activity?

The KB Activity aims to prevent new HIV infections and reduce vulnerability by addressing social, behavioral, and structural factors that contribute to HIV risk. A central emphasis is improving access to comprehensive sexual and reproductive health (SRH) services and strengthening community systems that support prevention and linkage to services.

4) Who are the priority populations for this activity?

The opportunity identifies two priority groups: orphans and vulnerable children (OVC) and adolescent girls and young women (AGYW).

5) What kinds of factors does the activity intend to address to reduce HIV risk?

The activity focuses on social, behavioral, and structural drivers of HIV risk, including challenges such as gender inequality, economic vulnerability, limited access to youth-friendly services, stigma, and barriers that prevent adolescents and vulnerable households from using prevention and SRH services.

6) Is this funding opportunity limited to clinical services?

No. The announcement states the activity is designed to support and complement the Government of Lesotho (GOL) multi-sector response to HIV and is not limited to clinical services alone. It emphasizes strengthening community platforms and systems that improve prevention, referrals, and service linkage.

7) What role do community-level systems play in the KB Activity?

Community-level systems are central to the design. The activity intends to strengthen community platforms that connect households and individuals to services, reinforce prevention messaging and risk reduction behaviors, and support district- and community-level rollout and scale-up of clinical interventions.

8) What types of activities are implied by the opportunity description?

Based on the description, programming may involve coordinated community-based prevention, referral and linkage systems, support for vulnerable households, and interventions that reduce barriers to care, with the intention that clinical services become more accessible, better utilized, and more sustainable.

9) How does the KB Activity align with the Government of Lesotho (GOL) response?

The activity is explicitly designed to support and complement the GOL multi-sector HIV response. It also signals a strong expectation that implementers coordinate with services funded by the GOL, PEPFAR, and other development partners to avoid duplication and integrate with existing systems.

10) How does this opportunity connect to PEPFAR and UNAIDS 95-95-95 goals?

Although the activity is prevention-focused, it is framed as a contributor to PEPFAR and UNAIDS 95-95-95 goals. The description notes that effective community engagement and strong service linkage can help people learn their status earlier, stay in care, and support adherence, which reduces onward transmission.

11) Which USAID strategy does the KB Activity contribute to?

The activity contributes to USAID/Southern Africa's Regional Development Cooperation Strategy, specifically Development Objective 2: "Reduced impact of HIV/AIDS on the region."

12) Where in Lesotho will the KB Activity be implemented?

The KB Activity is intended to be implemented across all ten districts of Lesotho. The districts are also identified as PEPFAR priority areas.

13) Is coordination with other funders and programs required?

Yes. The announcement states applicants are expected to coordinate closely with services already funded by the GOL, PEPFAR, and other development partners, indicating an expectation for collaboration, integration, and avoidance of duplication.

14) What is the intended timeframe for the KB Activity?

The opportunity describes a five-year effort.

15) What is the long-term public health aim mentioned in the announcement?

The shared goal highlighted is to significantly reduce the number of new HIV infections in Lesotho by 2020 and beyond, positioning the activity as part of a longer-term prevention and resilience strategy rather than a short-term pilot.

16) What funding mechanism will be used for this award?

This opportunity uses a Cooperative Agreement mechanism.

17) What does it mean that this is a Cooperative Agreement?

The description explains that a Cooperative Agreement typically means USAID anticipates substantial involvement during implementation, such as joint planning, technical collaboration, or close monitoring and learning.

18) Which USAID office issued this funding opportunity?

The opportunity was released by USAID (Agency for International Development, South Africa; USAID-Pretoria).

19) What is the opportunity number for this funding opportunity?

The opportunity number is 72067419RFA00005.

20) When was this opportunity created and when did it close?

The creation date is March 13, 2019, and the original closing date is April 18, 2019.

21) What is the maximum funding amount (award ceiling) stated?

The award ceiling listed is $35,000,000.

22) How many awards did USAID expect to make?

USAID expected to make one award.

23) What is the program area or category for this opportunity?

The activity category is Health.

24) What CFDA number is referenced?

The CFDA number referenced is 98.001.

25) Who is eligible to apply, based on the information provided?

Eligibility is listed broadly as "Others," with further clarification intended in the full announcement under the additional eligibility information section.

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