Opportunity Information: Apply for 72067419RFA00005
The Karabo ea Bophelo (KB) Activity in Lesotho is a USAID/Southern Africa funding opportunity designed to support a five-year, nationwide effort to prevent new HIV infections and reduce vulnerability among two priority groups: orphans and vulnerable children (OVC) and adolescent girls and young women (AGYW). "Karabo ea Bophelo" translates to "a solution to good health," and the activity is structured to align closely with Lesotho's HIV mitigation and prevention priorities while strengthening community-level systems that help people access and stay connected to health and social services.
At its core, the KB Activity focuses on addressing the social, behavioral, and structural factors that contribute to HIV risk, especially for OVC and AGYW. This includes the kinds of challenges that often sit behind infection risk and poor health outcomes, such as gender inequality, economic vulnerability, limited access to youth-friendly services, stigma, and barriers that keep adolescents and vulnerable households from using prevention and sexual and reproductive health (SRH) services. A major emphasis is placed on expanding and improving access to comprehensive SRH services as a practical way to reduce new infections and strengthen prevention outcomes over time.
The activity is explicitly designed to support and complement the Government of Lesotho (GOL) multi-sector response to HIV, meaning it is not limited to clinical services alone. Instead, it aims to strengthen community platforms that can connect households and individuals to services, reinforce prevention messaging and risk reduction behaviors, and support the local rollout and scale-up of clinical interventions. In practical terms, this type of programming often involves coordinated community-based prevention, referral and linkage systems, support for vulnerable households, and interventions that reduce barriers to care, with the intention that clinical services are more accessible, better utilized, and more sustainable at district and community levels.
KB also sits within broader U.S. Government and global HIV targets. It contributes to USAID/Southern Africa's Regional Development Cooperation Strategy, specifically Development Objective 2, "Reduced impact of HIV/AIDS on the region." It is also framed as a contributor to PEPFAR and UNAIDS 95-95-95 goals, which aim to ensure that the vast majority of people living with HIV know their status, receive sustained treatment, and achieve viral suppression. While KB is prevention-focused, the link to 95-95-95 reflects the reality that effective community engagement and service linkage are essential to finding people earlier, keeping them in care, and supporting adherence, all of which ultimately reduces onward transmission.
Geographically, the KB Activity is intended to be implemented across all ten districts of Lesotho, which are also identified as PEPFAR priority areas. Applicants are expected to coordinate closely with services already funded by the GOL, PEPFAR, and other development partners, which signals a strong expectation for collaboration, avoidance of duplication, and integration with existing district-level and national systems. The shared goal highlighted in the announcement is to significantly reduce the number of new HIV infections in Lesotho by 2020 and beyond, positioning the activity as part of a longer-term prevention and resilience strategy rather than a short-term pilot.
From the grant administration perspective, this opportunity was released by USAID (Agency for International Development, South Africa; USAID-Pretoria) as a discretionary funding opportunity using a Cooperative Agreement mechanism. A Cooperative Agreement typically means USAID anticipates substantial involvement during implementation, such as joint planning, technical collaboration, or close monitoring and learning. The opportunity number is 72067419RFA00005, with a creation date of March 13, 2019 and an original closing date of April 18, 2019. The award ceiling listed is $35,000,000, and USAID expected to make one award. The activity category is Health, and the CFDA number referenced is 98.001. Eligibility is listed broadly as "Others," with further clarification intended in the full announcement under the additional eligibility information section.Apply for 72067419RFA00005
- The Agency for International Development, South Africa USAID-Pretoria in the health sector is offering a public funding opportunity titled "Karabo ea Bophelo (KB) Activity in Lesotho" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 98.001.
- This funding opportunity was created on Mar 13, 2019.
- Applicants must submit their applications by Apr 18, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $35,000,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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